Structure of SARS-CoV-2 Mpro in complex with its degrader

Structure of SARS-CoV-2 Mpro in complex with its degrader Descriptor: (4-methoxyphenyl)methyl ~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]carbamate, 3C-like proteinase nsp5 Authors: Feng, Y, Li, W, Cheng, S.H, Li, X.B. Deposit date: 2024-03-06 Release date: 2024-09-04 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Development of novel antivrial agents that induce the degradation of the main protease of human-infecting coronaviruses. Eur.J.Med.Chem., 275, 2024