We aimed to study the molecular mechanisms of chronic obstructive pulmonary disease (COPD) caused by cigarette smoke more comprehensively and systematically through different perspectives and aspects
Rationale: Genome-wide association studies (GWAS) and candidate gene studies have identified a number of loci linked to susceptibility of chronic obstructive pulmonary disease (COPD), a smoking-relate
Microarray data, comparing age matched non-smokers, healthy smokers and COPD patients. Data from Durham AL. et al. "Regulation of Wnt4 in chronic obstructive pulmonary disease", FASEB J. (2013). doi 1
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. DNA methylation can regulate gene expression. Understanding the poten