Immunoglobulin UMI sequencing from human gut
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA596067
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资源简介:
To study the ontogeny of IgA2+ PCs and the clonal architecture of intestinal B cells in homeostasis we performed high-throughput Ig repertoire analysis with subclasses resolution of B cells and PCs sorted from the terminal ileum and ascending colon of four adults. In total, 10,182,511 Ig heavy chain variable (IGHV) gene sequences from 4 donors were obtained through next generation sequencing (NGS). To correct PCR and sequencing errors, cDNA molecules were labeled with unique molecular barcodes during library preparation
创建时间:
2019-12-17



