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Palladium-Catalyzed Direct C–H Trifluoroethylation of Aromatic Amides

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Figshare2017-08-07 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Palladium-Catalyzed_Direct_C_H_Trifluoroethylation_of_Aromatic_Amides/5281600
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A simple and direct C–H trifluoroethylation of aromatic amides has been developed. The protocol is applicable to a variety of aromatic amides, including ones derived from amino acids. The developed method can be used for further modifications of peptides. Preliminary mechanistic studies have been done by isolating the reaction intermediate.
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2017-08-07
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