LncRNA expression profile in hepar tissues of 12h after brain death or matched non-brain death donor liver transplantation

Brain death donor liver is an important organ source for liver transplantation.The liver injury after brain death donor liver transplantation is serious and the mechanism is unknown.In order to explore the role of lncRNAs and circRNAs expression profile and their biological functions in liver injury after brain death and liver transplantation, lncRNA and mRNA microarray expression profile were tested in the liver after brain death and normal liver transplantation.And this study lays a foundation for future studies on the potential role of lncRNAs in liver injury after brain death donor liver transplantation. To determine the LncRNA expression profile in hepar tissues of 12h after brain death donor liver transplantation and matched non-brain death donor liver transplantation, we uesed LncRNA microArray analysis form Arraystar to examine the expression of LncRNAs and circRNAs in hepar tissues of 12h after brain death donor liver transplantation and matched non-brain death donor liver transplantation. Hepar tissues from 12h after liver transplantation were distributed into two experimental groups: brain death donor liver transplantation group and matched non-brain death donor liver transplantation group, then perform LncRNAs chips by Arraystar Rat LncRNAs chip (Arraystar)