Target knockdown after systemic OTV administration in mice
收藏NIAID Data Ecosystem2026-05-01 收录
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Using single nucleus RNA sequencing, we knockdown of Malat1 across all cell types upon peripheral administration of OTV:Malat1. Overall design: TfR.KI mice received four weekly doses of 60mpk OTV:Malat1, nonTV:Malat1, Malat1 ASO (at an ASO-equivalent dose), or TV with no ASO. Tissues were harvested 72 hours after the final dose and snap frozen for molecuar analysis.
创建时间：
2024-02-12
