Human-specific Salmonella that causes Typhoid fever. Salmonella enterica subsp. enterica serovar Typhi str. Ty2

Salmonella enterica subsp. enterica serovar Typhi. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Salmonella enterica subsp. enterica serovar Typhi strain Ty2. This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development.