Genome-wide analysis of liver gene expression in prenatally undernourished male rat offspring under high-fat diet

Based on the developmental origin of health of disease hypothesis, we previously showed that prenatal 70% maternal food restriction (FR30) predisposes the offspring to development of pathologies in adulthood. In the present study, we focused on the liver gene expression profile of standard and high fat (HF)-fed FR30 adult offspring. Total RNA obtained from isolated liver of control standard and high-fat-fed adult offspring compared to prenatally undernourished (FR30) counterparts.