Modeling pancreatic beta cell senescence by induction of DNA double-strand breaks
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=f7a18eb21897f72bfaf46215878ce27a
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资源简介：
Pancreatic beta cell senescence occurs during the development of Type 1 Diabetes. To model the transcriptional responses of islet cells to DNA damage, we previously developed a human islet culture model in which the DNA damage response and senescence can be induced via double strand-breaks with the agent bleomycin. Here, we report the transcriptome-wide changes in human pancreatic islet cells following bleomycin exposure.
提供机构：
University of Manitoba
创建时间：
2022-02-20
