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Synthesis of Highly Functionalized Chiral 3,3′-Disubstituted Oxindoles via an Organocatalytic Enantioselective Michael Addition of Nitroalkanes to Indolylidenecyanoacetates

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Synthesis_of_Highly_Functionalized_Chiral_3_3_Disubstituted_Oxindoles_via_an_Organocatalytic_Enantioselective_Michael_Addition_of_Nitroalkanes_to_Indolylidenecyanoacetates/2565472
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资源简介:
An efficient bifunctional cinchona alkaloid derived thiourea-promoted enantioselective conjugate addition of nitroalkanes to indolylidenecyanoacetates has been developed under neat conditions. The process leads to synthetically interesting densely functionalized 3,3′-disubstituted oxindoles with creation of up to three stereogenic centers.
创建时间:
2016-02-22
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