MDDSymptoms

All summary statistics have the following columns:

CHR: chromosome

SNP: rsID of SNP

POS: base-pair coordinate

A1: effect allele

A2: other allele

MAF: minor allele frequency

OR: odds ratio of effect allele

SE: standard error of log(OR)

P: P value of association

N: sample size (which may differ between different SNPs due to missing genotypes at SNPs)

GWAS summary statistics are available for the following phenotypes:

1. PHQ9A1-A9: MDD symptoms in UK Biobank, based on PHQ9.

2. WorstEpisodeA1-A9 (no A5): WorstEpisode symptoms in UK Biobank, based on CIDI-SF.

3. dsPHQ9A3, A4, A6, A7, A8: PHQ9 symptoms down sampled to the same effective sample size as corresponding WorstEpisode.

4. dsWorstEpisodeA1, A2, A9: WorstEpisode symptoms down sampled to the same effective sample size as corresponding PHQ9 symptoms.

5. PHQ9SkipA3-A9: PHQ9 symptoms with a skip structure.

LifetimeMDD: lifetime MDD phenotype in 67K individuals in UK Biobank, as described in Cai et al 2020 Nature Genetics.