Crystal structure of TGFbRI complexed with an indolinone inhibitor
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Crystal structure of TGFbRI complexed with an indolinone inhibitor Descriptor: (3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]AMINO}METHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-6-CARBOXAMIDE, TGF-BETA RECEPTOR TYPE I Authors: Roth, G.J, Heckel, A, Brandl, T, Grauert, M, Hoerer, S, Kley, J.T, Schnapp, G, Baum, P, Mennerich, D, Schnapp, A, Park, J.E. Deposit date: 2010-03-03 Release date: 2010-10-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri) J.Med.Chem., 53, 2010
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2010-03-03
