Physiology and standard biochemistry in nine healthy volunteers before (0 h), during (4 h) and after (6 h) induction of experimental endotoxemia by means of a 4 h 0.5 ng/kg/hour LPS-infusion.

Data are presented as means±SD. Data from volunteers were compared by repeated-measures analyses (RM) and Tukey post hoc tests: pa, 0 h vs. 6 hb and 4 h vs. 6 hc. P-values HR, heart rate; MAP, mean arterial blood pressure; SpO2, peripheral oxygen saturation; SBE, standard base excess; WBC, white blood cells; CRP, c-reactive protein; AT, antithrombin; APTT, activated partial thromboplastin time; INR, international normalized ratio. NS, non-significant; ND, not done.