Fidaxomicin study of intestinal fibrosis

This includes a dataset of 10X genomics Visium spatial RNA sequencing of 3 CDS patients, a dataset of whole-transcriptome RNA sequencing of CD-HIFs, and a dataset of RayBiotech serum proteomics of patients., 10X Genomics Visium spatial RNA sequencing was done by UCLA TPCL and TCGB. The ileal tissues were obtained from UCLA Pathology.
Whole-transcriptome RNA sequencing was done by UCLA TCGB. CD-HIF RNA samples were obtained from Dr. Koon's laboratory.
Serum proteomics was done by RayBiotech. The sera were obtained from UCLA Pathology., , # Fidaxomicin study of intestinal fibrosis

Dataset DOI: [10.5061/dryad.ncjsxkt6q](10.5061/dryad.ncjsxkt6q)

## Description of the data and file structure

The serum proteomics file is in CSV format.

Column A is the protein name.

Columns B- H are percentage readings of each disease group, including healthy, stricturing CD (CDS), non-stricturing CD (CDNS), ulcerative colitis (UC), C. difficile infection (CDI), prediabetes (PD), and type 2 diabetes (T2DM).

Columns I-J are means and standard deviation of reading in columns B-H.

Columns K- P are the Z score of each disease group.

Columns Q-S are the gene names, Uniprot, and GeneIDs of each protein.

Column T is a description of each protein.

## Zenodo contents

Proper citation is required if the data are generated from commercial sources. Please consult the relevant companies for guidelines.

Two Zip folders are deposited on Zenodo. Zip files are under CC-BY licenses.

Please unzip the Zip folders to retrieve additional files of RNA s..., We do not provide personally identifiable information. All samples are coded. We could not obtain explicit consent from the participants because we did not have any information about the patients.