Top canonical pathways in PBMCs after 24 h treatment with 10% CSE.

PBMCs were treated for 24 hours with RPMI-1640 control medium (n = 6) or 10% CSE-conditioned medium (n = 6). Genes that were significantly modified by ≥1.5-fold, as assessed, using student's t-test followed by Benjamini-Hochberg FDR correction were imported into Ingenuity Pathway Analysis software. The table shows the top 5 canonical pathways identified from genes differentially expressed by ≥1.5-fold in PBMCs treated with 10% CSE. The P-value for association of genes and the described canonical pathways, and the ratio of significantly differentially expressed pathway components compared to the total components in that pathway was generated using Fisher's exact test.