Summary of geometry and SSs among CASP targets and SCOP folds considered as ‘New folds’.

aNumber of Smotifs with new geometrical classification after comparing with Smotifs extracted from protein structures already known.
bNumber of Smotifs that are formed by flanked secondary structures (FSS) of SS1, SS2 with unique lengths as compared to all previously known. For example, protein 1fw9 chain A was considered a new fold during CASP4 meeting (target id. T0086). It has a ββ motif between residues 73 and 95. The specific Smotif geometry was present in the backdated protein databank, but none of the Smotifs with the same geometry had two beta strands with comparable length (beta strand lengths are 10 and 11 residues for SS1 and SS2 respectively).