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Structure of HDAC2 in complex with an inhibitor (compound 14)

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Protein Data Bank Japan2024-05-22 更新2026-04-19 收录
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Structure of HDAC2 in complex with an inhibitor (compound 14) Descriptor: (1S)-N-[(1S)-7,7-dihydroxy-1-{4-[(1R,4S)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-6-yl]-1H-imidazol-2-yl}nonyl]-6-methyl-6-azaspiro[2.5]octane-1-carboxamide, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Klein, D.J, Yu, W. Deposit date: 2021-05-03 Release date: 2021-07-14 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation. Bioorg.Med.Chem.Lett., 47, 2021
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2021-05-03
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