Stereospecific Copper-Catalyzed Domino Ring Opening and sp<sup>3</sup> C–H Functionalization of Activated Aziridines with <i>N</i>‑Alkylanilines
收藏NIAID Data Ecosystem2026-03-10 收录
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资源简介:
Copper efficiently catalyzed nucleophilic ring opening, sp3 C–H functionalization, and C–N bond formation in the presence of tert-butyl hydroperoxide to afford functionalized imidazolidines starting from N-sulfonylaziridines and N-alkylanilines. The products were obtained in high optical purities (95 → 99% ee) with excellent functional group tolerance.
创建时间:
2016-12-15



