Synthesis of Thiazolines by Copper Catalyzed Aminobromination of Thiohydroximic Acids
收藏NIAID Data Ecosystem2026-03-08 收录
下载链接：
https://figshare.com/articles/dataset/Synthesis_of_Thiazolines_by_Copper_Catalyzed_Aminobromination_of_Thiohydroximic_Acids/2309254
下载链接
链接失效反馈官方服务：
资源简介：
A copper
catalyzed aminobromination of alkene tethered thiohydroximic
acids is described, providing a rapid approach to unnatural thiazoline
scaffolds not readily available via existing methods. Moderate to
high yields of bromothiazolines are obtained with alkyl- and aryl-substituted
thiohydroximic acid building blocks containing mono-, di-, and trisubstituted
alkenes. The reaction provides high levels of 5-exo selectivity, and
terminally monosubstituted alkenes result in predominant syn-diastereoselectivity.
创建时间：
2016-02-17
