Atherosclerosis Risk in Communities (ARIC) Cohort

The Atherosclerosis Risk in Communities (ARIC) Study, sponsored by the National Heart, Lung and Blood Institute (NHLBI), is a prospective epidemiologic study conducted in four U.S. communities. The four communities are Forsyth County, NC; Jackson, MS; the northwest suburbs of Minneapolis, MN; and Washington County, MD. ARIC is designed to investigate the etiology and natural history of atherosclerosis, the etiology of clinical atherosclerotic diseases, and variation in cardiovascular risk factors, medical care and disease by race, gender, location, and date. ARIC includes two parts: the Cohort Component and the Community Surveillance Component. The Cohort Component began in 1987, and each ARIC field center randomly selected and recruited a cohort sample of approximately 4,000 individuals aged 45-64 from a defined population in their community. A total of 15,792 participants received an extensive examination, including medical, social, and demographic data. These participants were examined with the baseline visit occurring in 1987-89, the second visit in 1990-92, the third visit in 1993-95, the fourth visit in 1996-98, the fifth visit in 2011-13, the sixth visit 2016-17, the seventh visit 2018-19 and the eighth visit 2020. Follow-up occurs yearly by telephone to maintain contact with participants and to assess health status of the cohort. In the Community Surveillance Component, these four communities were investigated to determine the community-wide occurrence of hospitalized myocardial infarction and coronary heart disease deaths in men and women aged 35-84 years. Hospitalized stroke is investigated in cohort participants only. Starting in 2006, the study conducted community surveillance of inpatient (ages 55 years and older) and outpatient heart failure (ages 65 years and older) for heart failure events beginning in 2005. Community Surveillance for non-cohorts ended in event year 2014. ARIC is currently funded through 2028. The ARIC Cohort is utilized in the following dbGaP sub-studies. To view genotypes, other molecular data, and derived variables collected in these sub-studies, please click on the following sub-studies below or in the "Sub-studies" section of this top-level study page phs000280 ARIC Cohort. phs000557 ARIC_CARe phs000090 GENEVA_ARIC phs000223 PAGE_CALiCo_ARIC phs000398 GO-ESP: HeartGo_ARIC phs000668 CHARGE_ARIC phs000860 MICORTEX phs001536 CCDG_ARIC phs003388 ARIC SomaScan ]]>
Annual Follow-Up Form (AFU Version A)Annual Follow-Up Form (AFU Version B)Annual Follow-Up Form (AFU Version C) & InstructionsAnnual Follow-Up Form (AFU Version D)Annual Follow-Up Form (AFU Version E)Annual Follow-Up Form (AFU Version F)Cohort Form, Annual Follow-Up (AFU) GCohort Form, Annual Follow-Up (AFU) HAnnual Follow-Up Form (AFU Version I)Annual Follow-Up Form (AFU Version J)Annual Follow-Up Form (AFU Version K)Annual Follow-Up Form (AFU Version L)Annual Follow-Up Form (AFU Version M)Cohort Manual, Exam 1, 2a. Cohort Procedures Appendix IX: Study FormsManual 7 - Blood Collection and Processing - Visit 4Manual 10 - Clinical Chemistry Determinations - Visit 1Manual 10 - Clinical Chemistry Determinations - Visit 2Manual 2 - Cohort Component Procedures - Visit 4Cohort Event Eligibility Form (CEL Version E)Common Hospital Information Form (CHI Version A)Confidential Data Form (CFD Version C)Coroner/Medical Examiner Form (COR Version C)Cohort Dictionary, Exam 1, Derived Variable DictionaryCohort Dictionary, Exam 2, Derived Variable DictionaryCohort Dictionary, Exam 3, Derived Variable DictionaryCohort Dictionary, Exam 4, Derived Variable DictionarySurveillance Form, Death Certificate Form (DTH)Manual 5 - Electrocardiography - Visit 1Anthropometry Form (ANT Version A)Dietary Intake Form (DTI Version A) & InstructionsFasting/Tracking Form (FTR Version A) & InstructionsHealth History Form (HHX Version C)Hematology Form (HMT Version A)Home Interview (HOM Version A)Household Enumeration Form (HEF Version A)Identification Form (IDN Version A) & InstructionsMedical History Form (MHX Version A) & InstructionsMedication Survey Form (MSR Version A) & InstructionsPhysical Examination Form (PHE Version A)Physician Questionnaire (PHQ Version A)Reproductive History Form (RHX Version A) & InstructionsRespiratory Symptoms/Physical Activity Form (RPA Version A) & InstructionsSitting Blood Pressure Form (SBP Version A) & InstructionsTIA/Stroke Summary Form (TSR Version A)Cohort Form, Exam 1, TIA/Stroke (TIA)Venipuncture Form (VEN Version A)Anthropometry Form (ANT Version B) & InstructionsCognitive Function Form (CNF Version A) & InstructionsDietary Intake Form (DTI Version B)Family History Form (FHX Version A) & InstructionsFasting/Tracking Form (FTR Version B) & InstructionsHealth and Life Profile (HPA, HPB, HPC Version A) & InstructionsHealth History Form (HHX Version B) & InstructionsHematology Form (HMT Version B) & InstructionsMedication Survey Form (MSR Version B) & InstructionsPhysical Examination Form (PHE Version B) & InstructionsPhysician Questionnaire Form (PHQ Version B)PPL Clinic Interview Form (PLC Version A), PPL Clinic Laboratory Form (PLL Version A)Physical Activity Form (PLA Version A)PPL Post-Clinic Interview Form (PLP Version A), PPL Screening Form (PLS Version A)Respiratory Symptoms Form (RPA Version B) & InstructionsSitting Blood Pressure Form (SBP Version B) & InstructionsTIA/Stroke Summary Form (TSR Version B) & InstructionsTIA/Stroke Form (TIA Version C) & InstructionsUpdate Form (UPD Version A) & InstructionsVenipuncture Form (VEN Version B) & InstructionsAnthropometry Form (ANT Version C)Cognitive Function Form (CNF Version B)Dietary Intake Form (DTI Version C)Fasting/Tracking Form (FTR Version C)Health History Form (HHX Version C)AFU Medical History Form (AMH Version A) & InstructionsMedication Survey Form (MSR Version C)MRI Procedure Form (MPR Version A)MRI Screening Form (MSC Version A)Personal History Form (PHX Version A)Report and Referral Form (REF Version A), ARIC Alert/Referral Log (ALT Version B)Reproductive History Form (RHX Version B)Physical Activity Form (RPA Version C) & InstructionsRetinal Examination Form (REX Version A)Sitting Blood Pressure Form (SBP Version C)TIA/Stroke Form (TIA Version D)Update Form (UPD Version B)Venipuncture Form (VEN Version C)Vitamin Survey Form (VIT Version A) & InstructionsAnthropometry Form (ANT Version D) & InstructionsCognitive Function Form (CNF Version C) & InstructionsFasting/Tracking Form (FTR Version D) & InstructionsHealth and Life Profile Form (HPC Version B) & InstructionsHealth History Form (HHX Version D) & InstructionsInflammation Form (INF Version A) & InstructionsInformed Consent Tracking Form (ICT Version A) & InstructionsMedical History Questionnaire (MHQ Version A)Medication Survey Form (MSR Version D) & InstructionsOral Glucose Tolerance Administration Form (GTA Version A)Oral Glucose Tolerance Screening Form (GTS Version A) & InstructionsOral Glucose Tolerance Screening Form (GTS Version B) & InstructionsPersonal History Form (PHX Version B)Physical Ability Questionnaire (PAQ Version A)Report and Referral Form (REF Version D), ARIC Alert/Referral Log (ALT Version B)Reproductive History Form (RHX Version C)Retinal Examination Form (REX Version B)Sitting Blood Pressure Form (SBP Version D)Socioeconomic Status Form (SES Version A)TIA/Stroke Form (TIA Version E)Surveillance Dictionary, Frozen CHD Variable DictionaryHeart Failure Diagnosis Form (HDX Version A)Surveillance Form, Heart Failure Hospital Record Abstraction with Supp. Info (HFS)Surveillance Form, Heart Failure Hospital Record Abstraction (HFA)Manual 9 - Hemostasis Determinations - Visit 1Surveillance Form, Hospital Record Abstraction (HRA)Informant Interview Form (IFI Version C)Manual 8 - Lipid and Lipoprotein Determinations - Visit 1Manual 8 - Lipid and Lipoprotein Determinations - Visit 3Cohort Dictionary, Exam 1, Modified Variable DictionaryCohort Dictionary, Exam 2, Modified Variable DictionaryCohort Dictionary, Exam 3, Modified Variable DictionaryCohort Dictionary, Exam 4, Modified Variable DictionarySurveillance Form, MMCC Community Final Diagnosis (MDX)Surveillance Form, No Form (NOF)Phantom Form (PTM Version B)ARIC Physical Activity MeasurementPhysician Heart Failure Form (PHF Version A-2010)Physician Questionnaire Form (PHQ Version C)Manual 11 - Sitting Blood Pressure - Visit 1Manual 11 - Sitting Blood Pressure - Visit 3Manual 11 - Sitting Blood Pressure - Visit 4Cohort Stroke Abstraction Form (STR Version D)Surveillance Event Inventory/Linkage Form (SXI Version D)Surveillance Dictionary, Incident CHD Variable DictionarySurveillance Dictionary, Incident Stroke Variable DictionaryManual 6A - Ultrasound Assessment Part A: Ultrasound Scanning - Version 1.0Manual 6a - Ultrasound Assessment: Scanning Procedures Visit 3 - Version 3.0Manual 6A - Ultrasound Assessment: Scanning Procedures Visit 4 - Version 4.0Cohort Manual, Exam 1, 2a. Cohort Procedures Appendix V: Scoring for the Physical Activity QuestionnaireCohort Manual, Exam 1, 2a. Cohort Procedures Appendix VI: Body Size MeasurementsManual 7 - Blood Collection and Processing - Visit 1Manual 2 - Cohort Component Procedures - Visit 1Manual 1 - General Description and Study Management - Visit 1Cohort Manual, Exam 4, 2. Cohort Procedures, Informed ConsentManual 4 - Pulmonary Function Assessment - Visit 1Manual 12 - Quality Assurance and Quality Control - Visit 1Manual 3 - Surveillance Component Procedures - Version 1.0Manual 6B - Ultrasound Assessment Part B: Ultrasound Reading - Version 1.0Cohort Form, Exam 1, Medical Data ReviewCohort Form, Exam 1, Annual Follow Up Record of Calls (TRC)Cohort Manual, Exam 1, 2a. Cohort Procedures Appendix IX: Management FormsARIC Cohort Annual Follow Up DescriptionAnnual Follow-Up Mapping TableAnnual Follow-Up Form (AFU Version C) InstructionsAnnual Follow-Up Form (AFU Version D) InstructionsAnnual Follow-Up Form (AFU Version H) InstructionsAnnual Follow-Up Form (AFU Version K) InstructionsAnnual Follow-Up Form (AFU Version L) InstructionsAnnual Follow-Up Form (AFU Version M) InstructionsManual 7 - Blood Collection and Processing - Visit 2Manual 7 - Blood Collection and Processing - Visit 3MMCC Cohort Final Diagnosis Form (CDX Version D)MMCC Cohort Final Diagnosis Form (CDX Version C) InstructionsCohort ECG Serial Change for Surveillance (CEA Version D)Cohort Event Eligibility Form (CEL Version E) InstructionsConfidential Data Form (CFD Version C) InstructionsCommon Hospital Information Form (CHI Version A) InstructionsManual 2 - Cohort Component Procedures - Visit 2Manual 2 - Cohort Component Procedures - Visit 3Manual 2 - Cohort Component Procedures - Visit 5Manual 2 - Cohort Component Procedures - Visit 1 - Appendix I-XICoroner/Medical Examiner Form (COR Version C) InstructionsDental Procedures Manual Version 1.0Dental History Form (DHS Version A)Dental Screening Form (DSR Version A)Death Certificate Form (DTH Version F)Death Certificate Form (DTH Version F) InstructionsManual 15 - Echocardiography - Visit 3Manual 5 - Electrocardiography - Visit 2Manual 5 - Electrocardiography - Visit 3Manual 5 - Electrocardiography - Visit 4Cohort Manual, Exam 1, 1. General Description and Study ManagementManual 1 - General Description and Study Management - Visit 3Manual 1 - General Description and Study Management - Visit 4Manual 1 - General Description and Study Management - Visit 5Heart Failure Diagnosis Form (HDX Version A) InstructionsManual 9 - Hemostasis Determinations - Visit 2Heart Failure Hospital Record Abstraction Form (HFA Version C)Heart Failure Hospital Record Abstraction Form (HFA Version C) InstructionsHeart Failure Hospital Record Abstraction Form with Supp. Info (HFS Version B)Heart Failure Hospital Record Abstraction Form with Supp. Info (HFS Version B) InstructionsHealth and Life Profile: Part B Data Book (HPB Version A)Health and Life Profile: Part C Data Book (HPC Version A)Hospital Abstraction Form (HRA Version F)Hospital Abstraction Form (HRA Versions A-F) Instructions Informant Interview Form (IFI Version A)Informant Interview Form (IFI Version C) InstructionsLaboratory Form (LAB Version B)Manual 8 - Lipid and Lipoprotein Determinations - Visit 2Manual 2 - Cohort Component Procedures - Visit 4 - ExcerptManual 14a - Retinal Photography - Visit 3Manual 3A - Surveillance of Heart Failure Version 2.1Manual 3 - Surveillance Component Procedures - Version 6.0Manual 3 - Surveillance Component Procedures AppendicesManual 2 - Cohort Component Procedures - Visit 1Manual 2 - Cohort Component Procedures - Visit 2Manual 2 - Cohort Component Procedures - Visit 3MMCC Community Final Diagnosis Form (MDX Version F)MMCC Community Final Diagnosis Form (MDX Version E) InstructionsPhysician Heart Failure Form (PHF Version A-2007) InstructionsPhysician Questionnaire Form (PHQ Version C-2010)Phantom Form (PTM Version B) InstructionsManual 4 - Pulmonary Function Assessment - Visit 2Manual 12 - Quality Assurance and Quality Control - Visit 2Manual 12 - Quality Assurance and Quality Control - Visit 3Manual 12 - Quality Assurance and Quality Control - Visit 4Manual 14a - Retinal Photography - Visit 3Manual 14b - Retinal Reading Protocol - Visit 3Stroke Final Diagnosis Form (SDX Version B)Manual 11 - Sitting Blood Pressure - Visit 2Cohort Stroke Abstraction Form (STR Version D) InstructionsManual 3 - Surveillance Component Procedures - Version 2.0Manual 3 - Surveillance Component Procedures - Visit 3Manual 3 - Surveillance Component Procedures - Version 4.0Manual 3 - Surveillance Component Procedures - Version 6.2Manual 3A - Surveillance of Heart Failure Version 2.1Surveillance Event Inventory/Linkage Form (SXI Version D) InstructionsTransient Ischemic Attack Form (TIA Versions A-B) & InstructionsTIA/Stroke Form (TIA Version B)Manual 6C - Ultrasound Assessment: Arterial Distensibility Tracking ProceduresManual 6D - Ultrasound Assessment: Distensibility Reading ProceduresManual 6B - Ultrasound Assessment: Ultrasound Reading Procedures for Visit 2 - Version 2.0Manual 6b - Ultrasound Assessment: Reading Procedures Visit 3 - Version 3.0Manual 6B - Ultrasound Assessment: Reading Procedures Visit 4 - Version 1.0Manual 6A - Ultrasound Assessment: Ultrasound Scanning Procedures for Visit 2 - Version 2.0Ankle Brachial Index Data Book (ABI04 Cohort Exam 1)Ankle Brachial Index Data Book (ABI34 Cohort Exam 3)Ankle Brachial Index Data Book (ABI44 Cohort Exam 4)Nutrition Derived Variables Data Book (ANUT2 Cohort Exam 1)Atrial Fibrillation Data Book (ATRFIB11 Cohort Exam 1)Atrial Fibrillation Data Book (ATRFIB21 Cohort Exam 2)Atrial Fibrillation Data Book (ATRFIB31 Cohort Exam 3)Atrial Fibrillation Data Book (ATRFIB41 Cohort Exam 4)Ankle Brachial Data Book (BPU01 Cohort Exam 1)Blood Pressure Data Book (BPUA03 Cohort Exam 3)Blood Pressure Data Book (BPUB04 Cohort Exam 4)Chemistry Data Book (CHMA Cohort Exam 1)Chemistry Data Book (CHMB Cohort Exam 2)Cognitive Function Data Book (CNFA Cohort Exam 2)Cognitive Function Data Book (CNFC04 Cohort Exam 4)ECG Data Book (ECGC Cohort Exam 2)ECG Data Book (ECGD04 Cohort Exam 3)ECG Data Book (ECGE04 Cohort Exam 4)ECG Data Book (ECGMA03_0 Cohort Exam 1)ECG Data Book (ECGMB22 Cohort Exam 2)ECG Data Book (ECGMC35 Cohort Exam 3)ECG Data Book (ECGMD41 Cohort Exam 4)ECG Data Book (ECGX02 Cohort Exam 1)ECG Data Book (ECHA04 Cohort Exam 3, Jackson Only)ECG Data Book (ERHA Cohort Exam 1)ECG Data Book (ESHA Cohort Exam 2)ECG Data Book (ESMA04 Cohort Exam 2)ECG Data Book (ESMB07 Cohort Exam 3)ECG Data Book (ESMC03 Cohort Exam 4)ECG Data Book (ETLA Cohort Exam 1)ECG Data Book (ETLB Cohort Exam 2)ECG Data Book (ETLC04 Cohort Exam 3)ECG Data Book (ETLD04 Cohort Exam 4)Hemostatis Data Book (HEMA Cohort Exam 1)Hemostatis Data Book (HEMC31 Cohort Exam 3)Medication Data Book (HHXCOD22 Cohort Exam 2)Blood Draw Data Book (HMTCV301 Cohort Exam 3)Blood Draw Data Book (HMTCV401 Cohort Exam 4)Lipid Data Book (LIPA Cohort Exam 1)Lipid Data Book (LIPB Cohort Exam 2)Lipid Data Book (LIPC04 Cohort Exam 3)Lipid Data Book (LIPD04 Cohort Exam 4)Medical History Questionnaire Data Book (MHQA04 Cohort Exam 4)MRI Procedure Data Book (MPRA04 Cohort Exam 3)MRI Screening Data Book (MSCA04 Cohort Exam 3)Medication Data Book (MSRCOD07 Cohort Exam 1)Medication Data Book (MSRCOD26 Cohort Exam 2)Medication Data Book (MSRCOD36 Cohort Exam 3)Medication Data Book (MSRCOD43 Cohort Exam 4)Nutrient Data Book (NUTV2 Cohort Exam 2)Nutrient Data Book (NUTV2X Cohort Exam 2)Nutrient Data Book (NUTV3 Cohort Exam 3)Nutrient Data Book (NUTV3X Cohort Exam 3)Physical Ability Questionnaire Data Book (PAQA04 Cohort Exam 4)Pulmonary Function Data Book (PFTA Cohort Exam 1)Pulmonary Function Data Book (PFTB Cohort Exam 2)Personal History Data Book (PHXA04 Cohort Exam 3)Personal History Data Book (PHXB04 Cohort Exam 4)Pulmonary Data Book (PULM Cohort Exam 1)Pulmonary Function Assessment Data Book (PULM21 Cohort Exam 2)Retinal Examination Data Book (REXA04 Cohort Exam 3)Reproductive History Data Book (RHXC04 Cohort Exam 4)Medication Data Book (RHXCOD05 Cohort Exam 1)Medication Data Book (RHXCOD32 Cohort Exam 3)Medication Data Book (RHXCOD42 Cohort Exam 4)Apolipoprotein A-I in Plasma by Radioimmunoassay Data Book (RIAA Cohort Exam 2)Retinal Image Data Book (RIPA04 Cohort Exam 3)Retinal Image Data Book (RIPB02 Cohort Exam 4)Retinal Examination Light Box Data Book (RLBA04 Cohort Exam 3)Ultrasound Data Book (RTABF03 Cohort Exam 1)Ultrasound Data Book (RTABF25 Cohort Exam 2)Ultrasound Data Book (RTABF34 Cohort Exam 3)Ultrasound Data Book (RTABF42 Cohort Exam 4)Ultrasound Data Book (RTABM03 Cohort Exam 1)Ultrasound Data Book (RTABM25 Cohort Exam 2)Ultrasound Data Book (RTABM34 Cohort Exam 3)Ultrasound Data Book (RTABM42 Cohort Exam 4)Ultrasound Data Book (RTASBF24 Cohort Exam 2)Ultrasound Data Book (RTASBF33 Cohort Exam 3)Ultrasound Data Book (RTASBF42 Cohort Exam 4)Ultrasound Data Book (RTASBM24 Cohort Exam 2)Ultrasound Data Book (RTASBM33 Cohort Exam 3)Ultrasound Data Book (RTASWF24 Cohort Exam 2)Ultrasound Data Book (RTASWF33 Cohort Exam 3)Ultrasound Data Book (RTASWF42 Cohort Exam 4)Ultrasound Data Book (RTASWM24 Cohort Exam 2)Ultrasound Data Book (RTASWM33 Cohort Exam 3)Ultrasound Data Book (RTASWM42_0 Cohort Exam 4)Ultrasound Data Book (RTAWF03 Cohort Exam 1)Ultrasound Data Book (RTAWF25 Cohort Exam 2)Ultrasound Data Book (RTAWF34 Cohort Exam 3)Ultrasound Data Book (RTAWF42 Cohort Exam 4)Ultrasound Data Book (RTAWM03 Cohort Exam 1)Ultrasound Data Book (RTAWM25 Cohort Exam 2)Ultrasound Data Book (RTAWM34 Cohort Exam 3)Stroke Data Book (STROKE01 Cohort Exam 1)Stroke Data Book (STROKE2 Cohort Exam 2)Stroke Data Book (STROKE32 Cohort Exam 3)Stroke Data Book (STROKE41 Cohort Exam 4)Nutrient Data Book (TOTNUTX Cohort Exam 1)Ultrasound Data Book (UBMD4 Cohort Exam 1)Ultrasound Data Book (UBMDALL Cohort Exam 1)Ultrasound Data Book (UBMDBF02 Cohort Exam 1)Ultrasound Data Book (UBMDBM02 Cohort Exam 1)Ultrasound Data Book (UBMDWF02 Cohort Exam 1)Ultrasound Data Book (UBMDWM02 Cohort Exam 1)Ultrasound Data Book (UBME4 Cohort Exam 2)Ultrasound Data Book (UBMEBF4 Cohort Exam 2)Ultrasound Data Book (UBMEBM4 Cohort Exam 2)Ultrasound Data Book (UBMEWF4 Cohort Exam 2)Ultrasound Data Book (UBMEWM4 Cohort Exam 2)Ultrasound Data Book (UBMF04 Cohort Exam 3)Ultrasound Data Book (UBMFBF02 Cohort Exam 3)Ultrasound Data Book (UBMFBM02 Cohort Exam 3)Ultrasound Data Book (UBMFWF02 Cohort Exam 3)Ultrasound Data Book (UBMFWM02 Cohort Exam 3)Ultrasound Data Book (UBMG42 Cohort Exam 4)Ultrasound Data Book (UBMGBF01 Cohort Exam 4)Ultrasound Data Book (UBMGBM01 Cohort Exam 4)Ultrasound Data Book (UBMGWF01 Cohort Exam 4)Ultrasound Data Book (UBMGWM01 Cohort Exam 4)Ultrasound Data Book (UDTA Cohort Exam 1)Ultrasound Data Book (UDTB Cohort Exam 2)Vitamin and Nutrient Data Book (VITNUT01 Cohort Exam 3)Cohort Surveillance CHD Events Data Dictionary (C07EVT1)Cohort Surveillance Stroke Derived Variable Dictionary (C07DERV1)Aged 45-64 at baseline]]>
The cohort was examined at 7 clinic visits: Visit 1: 1987-89 Visit 2: 1990-92 Visit 3: 1993-95 Visit 4: 1996-98 Visit 5: 2011-13Visit 6: 2016-17Visit 7: 2018-19Visit 8 (telephone only): 2020]]>