Analysis of the nuclear export activity of putative NES sequences within ataxin-3 primary structure.
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Aliphatic residues fitting the consensus NES sequence ΦX1–3ΦX2–3ΦXΦ (where Φ indicates a large hydrophobic residue, and X indicates any amino acid) are highlighted in bold. The tested putative NESs in Atx3 did not show detectable nuclear export activity, as assessed using the Rev(1.4)-GFP nuclear export assay.
创建时间:
2015-12-02



