Population and single cell receptive field maps from mouse visual cortex

In this study we use population receptive-field (pRF) mapping techniques, which allow estimates to be made of aggregate receptive field sizes, to map the visual cortex of mice using wide-field calcium imaging. We include data relating the position of the pRF to its size across visual cortex. These maps show a region of mouse visual cortex in which pRFs are considerably smaller. We investigated the source of the smaller pRFs by recording receptive-fields from multi-units in the different layers of V1 using laminar electrodes and by using two-photon imaging to tile almost the entirety of V1 at the single-cell level. We also examine the relationship between RF position and size in the higher visual areas that surround V1 including LM, RL, AL, Am and PM.