Results for SNPs showing suggestive evidence of association (P−5) in the primary (European-ancestry) meta-analysis of early AMD.

Where multiple correlated SNPs in the same gene/region showed similar association evidence, the most strongly associated SNP is shown.aNCBI Human Genome Build 36.3 coordinates;bEffective allele;cFrequency of the effective allele;dEstimated odds ratio and 95% confidence interval for the effect of each additional copy of the effective allele, based on the fixed-effects, inverse variance-weighted meta-analysis of European-ancestry cohorts;eP-value associated with the estimated OR;fHeterogeneity I2 statistic;gHeterogeneity P-value, based on Cochran’s Q statistic;hwithin a 500 kb genomic region centred on the associated SNP.