Vertebrate Gene Nomenclature Committee
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The Vertebrate Gene Nomenclature Committee (VGNC) is an extension of the established HGNC (HUGO Gene Nomenclature Committee) project that names human genes. VGNC is responsible for assigning standardized names to genes in selected vertebrate species that lack a nomenclature authority; currently these are chimpanzee, macaque, dog, cat, cattle, pig and horse. The VGNC also coordinates with the existing vertebrate nomenclature committees, MGNC (mouse), RGNC (rat), CGNC (chicken), XNC (Xenopus frog) and ZNC (zebrafish), to ensure genes are named in line with their human homologs.
脊椎动物基因命名委员会(Vertebrate Gene Nomenclature Committee,VGNC)是已成熟运行的人类基因命名项目——人类基因命名委员会(HUGO Gene Nomenclature Committee,以下简称HGNC)的延伸分支,该委员会负责为人类基因拟定标准化命名。VGNC的核心职责是为尚未设立专属基因命名管理机构的选定脊椎动物物种分配标准化基因名称,当前涵盖的物种包括黑猩猩、猕猴、犬、猫、牛、猪与马。此外,VGNC还与现有各脊椎动物命名委员会保持协作,包括小鼠基因命名委员会(Mouse Gene Nomenclature Committee,MGNC)、大鼠基因命名委员会(Rat Gene Nomenclature Committee,RGNC)、鸡基因命名委员会(Chicken Gene Nomenclature Committee,CGNC)、爪蟾蛙基因命名委员会(Xenopus Gene Nomenclature Committee,XNC)以及斑马鱼基因命名委员会(Zebrafish Gene Nomenclature Committee,ZNC),以确保各物种基因的命名与其人类同源基因保持统一规范。




