Description of lesion development when TMPRSS2-ERG is crossed with Nkx3.1-/- and Pten+/- transgenic lines.
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The numbers of mice displaying the indicated lesions relative to the number of mice analyzed is shown. The values in parentheses correspond to the average number of lesions per prostate where a significant increase in mPIN was observed in A5/Pten+/- compared to Pten+/- at 28 weeks.ap≤0.05.bNumbers of lesions per animal ranged from 0–17b p = 0.15.
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2015-12-02



