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X-ray structure of the complex between human alpha thrombin and the duplex/quadruplex aptamer M08s-1_41mer

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Protein Data Bank Japan2024-10-16 更新2026-03-28 收录
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X-ray structure of the complex between human alpha thrombin and the duplex/quadruplex aptamer M08s-1_41mer Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, M08s-1_41mer, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Troisi, R, Napolitano, V, Sica, F. Deposit date: 2022-12-06 Release date: 2023-07-19 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide. Nucleic Acids Res., 51, 2023
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2022-12-06
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