Predictive capability assessment for different prediction scenarios in both original and refined models.

S and PM indicate the prediction interval score and proportion of measurements within the prediction envelope and are reported for prediction of steady-state BV response (150-180 min, i.e., S150 − 180 and PM150−180), prediction of transient response (45-80 min, i.e., S45−80 and PM45−80), and leave-one-out prediction (i.e., SLeave-One-Out and PMLeave-One-Out). P-values for the S and PM are obtained using paired t-test and Chi-squared test, respectively. Underline bold numbers indicates significant difference between the two models.