KRAS G12D in complex with MRTX-1133
收藏Protein Data Bank Japan2023-10-18 更新2026-03-28 收录
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KRAS G12D in complex with MRTX-1133 Descriptor: 4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... Authors: Gunn, R.J, Thomas, N.C, Xiaolun, W, Lawson, J.D, Marx, M.A. Deposit date: 2021-08-05 Release date: 2021-12-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS G12D Inhibitor. J.Med.Chem., 65, 2022
创建时间：
2021-08-05
