Raw data underlying the publication: Eco-Evolutionary Divergence in Pantoea ananatis Unveils Intrinsic Genomic-Metabolic

The dataset encompasses genomic, metabolomic, and phenotypic data from 18 <em>Pantoea ananatis</em> isolates derived from mulberry (<em>Morus</em> spp.), focusing on eco-evolutionary mechanisms underlying their pathogen-probiotic duality. Key findings include three genetic clades: low-virulence probiotics (Pa-I, 11 strains), high-virulence pathogens (Pa-II, 5 strains), and transitional (Pa-III, 2 strains). Representative strains Pa-6 (probiotic) and YSFJ (pathogen) highlight divergences in genome architecture (e.g., plasmids, pseudogenes), metabolomes (e.g., TCA/amino acid vs. phosphonate/sulfur pathways), pan-genome openness, multidrug resistance, and host interactions (e.g., mild colonization enhancing resilience vs. aggressive lysis accelerating dysbiosis). This supports predictive frameworks for biocontrol and resilient microbiome engineering in agriculture. Data types include raw sequencing reads, MS spectra, bioassay results, and figure sources, organized by category. Total size: approximately 10-15 GB. Ethical compliance: Biosafety protocols followed; no human/animal subjects. Contact corresponding authors for interpretation queries on genomic evolution or metabolomic networks.

该数据集涵盖了分离自桑树属（Morus spp.）的18株菠萝泛菌（Pantoea ananatis）分离株的基因组学、代谢组学及表型组学数据，旨在揭示其兼具病原菌与益生菌双重属性背后的生态进化机制。核心研究结果划分出三个遗传进化支：低毒力益生型（Pa-I，11株）、高毒力致病型（Pa-II，5株）以及过渡型（Pa-III，2株）。益生型代表菌株Pa-6与致病型代表菌株YSFJ凸显出多维度的显著差异，包括基因组结构（如质粒、假基因）、代谢组特征（如三羧酸循环（TCA）与氨基酸代谢通路、膦酸盐与硫代谢通路的差异）、泛基因组开放性、多药耐药性以及宿主互作模式（如温和定殖可增强宿主抗性，而剧烈裂解则会加速菌群失调）。本数据集可为农业生物防治及稳定菌群工程提供预测性理论框架。数据集包含按类别整理的原始测序读段、质谱（Mass Spectrometry，MS）谱图、生物测定结果及图片源文件，总数据量约为10-15 GB。伦理合规性方面：本研究严格遵循生物安全规程，未涉及人类或动物受试对象。若您对基因组进化或代谢组网络相关的解读存在疑问，请联系通讯作者。