Chromatin dynamics of p53 binding sites in IMR90. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA253315
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资源简介:
We report the chromatin modification dynamics at p53 binding sites upon treatment with DMSO or nutlin3-a (5uM) in IMR90 human lung fibroblasts using ChIP-seq and RNA-seq analyses. We assessed the genomewide changes in H3, H3K4me3, H3K4me2, H3K4me1, H3K27ac, H4K16ac, RNA polymerase II, and p53 in response to p53 activation. Overall design: ChIP-seq of 8 histone modifications or proteins for 2 conditions in 1 cell line.
创建时间:
2014-06-23



