Lipids impair NK cell anti-tumor immunity and transcription
收藏NIAID Data Ecosystem2026-05-02 收录
官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2024-09-03
相关数据集
Effect of chronic epinephrine exposure on gene expression in MIN6 cells
Chronic exposure to epinephrine enhances the compensatory insulin secretion in MIN6 cells while persistently inhibiting cell proliferation. The molecular mechanisms underlying these phenomena were inv
NIAID Data Ecosystem30
DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip
IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s
NIAID Data Ecosystem30
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.
Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated
NIAID Data Ecosystem10
D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses
Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up
NIAID Data Ecosystem30
Additional file 2 of DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections
Additional file 2. Supplementary Table 1. Description of animals used for characterization of DNA methylation during SIV infection.
NIAID Data Ecosystem30
