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Nanoparticle-mediated Targeting of the Fusion Gene RUNX1/ETO in t(8;21)-positive Acute Myeloid Leukemia [ATAC-seq]

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NIAID Data Ecosystem2026-05-02 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP601310
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资源简介:
To investigate the therapeutic potential of targeting RUNX1/ETO with lipid nanoparticles encapsulating chemically modefied siRNA. Chromatin Accessibility (ATAC-seq) was performing on cells lines after lipid nanoparticles in vitro. Overall design: Comparative chromatin accessibilty from in vitro treatment with active siRNA against RUNX1/ETO (LNP/siRE-mod) and control siRNA (LNP/siMM-mod).
创建时间:
2025-07-21
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