Crystal structure of BACE1 with its inhibitor
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Crystal structure of BACE1 with its inhibitor Descriptor: Beta-secretase 1, SULFATE ION, ethyl 1-{(2S,3S)-3-[(3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-[methyl(methylsulfonyl)amino]benzoyl)amino]-2-hydroxy-4-phenylbutyl}-1H-pyrazole-4-carboxylate Authors: Chen, T.T, Chen, W.Y, Xu, Y.C. Deposit date: 2011-11-21 Release date: 2012-11-21 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD simulations to be published
创建时间:
2011-11-21



