Human DNA Topoisomerase I (70 Kda) In Non-Covalent Complex With A 22 Base Pair DNA Duplex Containing an 8-oxoG Lesion

Protein Data Bank Japan2024-02-14 更新2026-03-21 收录

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Human DNA Topoisomerase I (70 Kda) In Non-Covalent Complex With A 22 Base Pair DNA Duplex Containing an 8-oxoG Lesion Descriptor: 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*(8OG)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*CP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I Authors: Lesher, D.T, Pommier, Y, Stewart, L, Redinbo, M.R. Deposit date: 2002-05-08 Release date: 2002-08-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.14 Å) Cite: 8-Oxoguanine rearranges the active site of human topoisomerase I Proc.Natl.Acad.Sci.USA, 99, 2002

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2002-05-08