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NHGRI Analysis, Visualization, and Informatics Lab-space

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知名数据库2026-06-02 收录
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The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL) is a unified computing environment for genomics data storage, management, and analysis. The AnVIL is a federated cloud platform designed to manage and store genomics and related data, enable population-scale analysis, and facilitate collaboration through the sharing of data, code, and analysis results. By inverting the traditional model of data sharing, the AnVIL eliminates the need for data movement while also adding security measures for active threat detection and monitoring and provides scalable, shared computing resources for any researcher. The core data management and analysis components of the AnVIL currently consists of Terra, Gen3, Galaxy, RStudio/Bioconductor, Dockstore, and Jupyter. In addition, several flagship genomics datasets are available within the AnVIL. The AnVIL is intended to create opportunities for analysis, collaboration, and data sharing that are needed to drive research and to make discoveries through the joint analysis of genomes together with associated clinical and molecular data types.

美国国家人类基因组研究所(NHGRI)基因组数据科学分析、可视化与信息学实验室空间(AnVIL)是一款面向基因组数据存储、管理与分析的统一计算环境。AnVIL是一款联邦云平台,旨在对基因组及相关数据进行管理与存储、支持群体规模分析,并通过共享数据、代码与分析成果促进科研协作。该平台通过颠覆传统的数据共享模式,无需进行数据迁移,同时增设了面向主动威胁检测与监控的安全防护机制,并可为所有研究人员提供可扩展的共享计算资源。目前AnVIL的核心数据管理与分析组件涵盖Terra、Gen3、Galaxy、RStudio/Bioconductor、Dockstore及Jupyter。此外,AnVIL平台内还提供了多款旗舰级基因组数据集。AnVIL旨在创造分析、协作与数据共享的机遇,以通过基因组与关联临床、分子数据类型的联合分析推动科研进展并实现科学发现。

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NHGRI Analysis, Visualization, and Informatics Lab-space 数据集图片
背景与挑战
背景概述
NHGRI AnVIL是一个联邦云平台,为基因组数据提供存储、管理和分析环境,支持大规模协作研究。它整合了Terra、Galaxy、Bioconductor等工具,并托管了包括1000 Genomes和GTEx在内的多个大型基因组数据集,总计超过4.7PB的数据和29.3万参与者。该平台通过安全、可扩展的云资源,消除了数据移动需求,促进了数据共享和可重复分析。
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