官方服务:
资源简介:
BRCA1 depletion effect on HeLa cells
应用场景:
创建时间:
2010-06-23
相关数据集
Chromosome instability in tumor cells due to defects in Aurora B mediated error correction at kinetochores
We characterized a panel of cancer cells and found that they exhibited chromosome instability (CIN) that was associated with high frequencies of aberrant kinetochore:microtubule attachments. Failure t
DataCite Commons2020-08-28 更新80
Transcription profiling of HSCs from SYCNRIP WT and KO mice. Transcription profiling of HSCs from SYCNRIP WT and KO mice
SYNCRIP depletion results in HSCs losing their self renewal abilities. Next generation sequencing was conducted in SYNCRIP WT and KO HSCs to investigate the transcriptional changes that occur, and res
NIAID Data Ecosystem60
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε
Vaccinia-related kinase 1 (VRK1) and the δ and ε isoforms of casein kinase 1 (CK1) are linked to various disease-relevant pathways. However, the lack of tool compounds for these kinases has significan
NIAID Data Ecosystem40
Whole-genome expression analysis of Rnaseh2b(E202X/E202X) embryos. Mus musculus
The transcriptome of E9.5 embryos lacking functional RNase H2 (Rnaseh2bE202X/E202X) was compared to age-matched wild type controls to investigate the molecular basis of growth arrest in Rnaseh2-/- mic
NIAID Data Ecosystem70
Splicing Variation Contributes to Functional Dysregulation of Genes in Acute Myeloid Leukemia
Acute Myeloid Leukemia (AML) has been associated with somatic mutations in numerous genes; however, the penetrance of these mutations is low. Here we investigate the contribution of alternative splici
NIAID Data Ecosystem60



