Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC
收藏Protein Data Bank Japan2023-08-16 更新2026-03-21 收录
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Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-(4-{[(2-AMINO-4-OXO-3,4-DIHYDROQUINAZOLIN-6-YL)AMINO]SULFONYL}BENZOYL)GLUTAMIC ACID, ... Authors: Cheong, C.G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A. Deposit date: 2003-06-06 Release date: 2004-04-27 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structures of Human Bifunctional Enzyme Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase in Complex with Potent Sulfonyl-containing Antifolates. J.Biol.Chem., 279, 2004
创建时间：
2003-06-06
