De novo generation of macrophage from placenta-derived hemogenic endothelium
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE152903
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资源简介：
We profile the transcriptional landscape of mouse fetal placenta and identify four distinct types of haematopoietic stem/progenitor cells (HSPCs) during mid-gestation using single-cell RNA sequencing. We experimentally validate and uncover that a subpopulation of placental endothelial cells exhibits hemogenic endothelial (HE) potential and shares transcriptional features with HE cells in the aorta-gonad-mesonephros (AGM) region. Examination of gene expressive levels in sorting placental cells, placental HE cells, AGM HE cells, placental ECs, AGM ECs and yolk sac ECs from pregnant mice.
创建时间：
2021-09-30
