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Stereoselective Synthesis of 1‑Methyl-3′,4′,5′,6′-tetrahydrospiro[indoline-3,2′-pyran]-2-one Derivatives via Prins Cyclization

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Figshare2016-02-13 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Stereoselective_Synthesis_of_1_Methyl_3_4_5_6_tetrahydrospiro_indoline_3_2_pyran_2_one_Derivatives_via_Prins_Cyclization/2160904
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资源简介:
A novel spirocyclization has been developed for the construction of functionalized spirooxindole pyran via Lewis acid promoted Prins cyclization. The reaction proceeds through formation of a single diastereoisomer with high stereoselectivity. This approach can be used to construct biologically important substituted spirooxindole as well as fluorinated pyran scaffolds.
创建时间:
2016-02-13
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