Comprehensive insights into sepsis-induced cardiac dysfunction through proteomics and metabolomics

The CLP mice were utilized as a model in this study to investigate the impact of septic cardiomyopathy on the molecular changes in heart tissues through combining metabolomics and proteomics studies. This work adds to our understanding of the implications of sepsis-induced cardiac dysfunction and may lead to identifying novel potential biomarkers and a better understanding of sepsis pathophysiology.