Source data of the manuscript "Exploiting pleiotropy to enhance variant discovery with functional false discovery rates"

This repository contains the data to reproduce Figures 2-5 in the manuscript "Exploiting pleiotropy to enhance variant discovery with functional false discovery rates." Below is a brief overview of the figures: Figure 2. Simulation results for the sfFDR framework in the independent SNP simulation study when the primary study power is ``Medium.'' Figure 3. Comparing the functional $p$-value from sfFDR to the $p$-value from MTAG and the standard $p$-value from a GWAS analysis of BMI in the UK Biobank. Figure 4. Significance results for the EGPA study under the null hypothesis of no association between genotype and disease. Figure 5. Manhattan plot of the standard $p$-values and the functional $p$-values from sfFDR in the EGPA study.