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Pharmacological Repositioning of the transcription factor PU.1 [PRO-seq]

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NIAID Data Ecosystem2026-05-02 收录
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This study aims to investigate the effects of PU.1 binding-site inhibitors/redistributors (DB2115) upon nascent transcription in AML cell lines Overall design: The MOLM-13 cell line were treated with 5uM of DB compound for 0,1, 4 & 12hr, before cells were harvested for Precision nuclear run on and sequencing (PRO-seq).

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2024-12-14
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