Dataset for HADS manuscript

Rheumatoid arthritis (RA) patients have a greater prevalence of anxiety and depression. Proinflammatory cytokines are elevated in RA. We aim to evaluate the association between systemic inflammation in RA and anxiety and depression. Serum proinflammatory cytokines were measured, including interleukin (IL)‐6, IL‐17, and Tumour Necrosis Factor-alpha (TNF‐α). Among 31 patients, ten patients showed anxiety symptoms, 19 patients showed depression symptoms, and two displayed mixed symptoms. Serum TNF-α levels were significantly higher in active disease than in the remission group. There was no association and correlation between proinflammatory cytokines to anxiety and depression symptoms in the active disease and remission groups. This finding suggests that other factors besides disease activity and state of systemic inflammation may cause anxiety and depression in RA patients