JNK1 covalently bound to RU135 cyclohexenone based inhibitor
收藏Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8pt8
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JNK1 covalently bound to RU135 cyclohexenone based inhibitor Descriptor: GLYCEROL, Mitogen-activated protein kinase 8, methyl (1R,3R)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methylcarbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate Authors: Sok, P, Poti, A, Remenyi, A. Deposit date: 2023-07-13 Release date: 2024-07-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads. Nat Commun, 15, 2024
创建时间：
2023-07-13
