Association of duration of treatment with success versus failure/relapse—patients grouped by treatment history.

n, number of patients in subgroup of interest. aOR, adjusted odds ratios—adjustment described in footnotes for Table 3. Success, defined as cure or treatment completion and is compared to failure or relapse (see methods for definitions). Other outcomes of death and default not assessed in this analysis because in some datasets shorter duration that was directly due to death or default could not be identified. Past treatment, prior MDR means past treatment for more than 1 mo with two or more second-line drugs. No prior MDR includes all other treatment history.aVariance of the random intercepts and slopes high—so heterogeneity likely important. (See Tables S1–S12 for actual values).bVariance of the random intercepts and slopes low—so heterogeneity not likely to be important. (See also Tables S1–S12 for actual values).