Global gene expression changes in the lung and ileum of hyperoxia-exposed neonatal mice

Ths study addressed the hypothesis that exposure to hyperoxia alters gene expression in both the lung and the ileum, but that the gene epxression cahnges are specific to each organ. The data indicat ethat there are highly specific changes in each organ due to hyperoxia. Neonatal mice were exposed from postnatal day 3 (P3) to P14 to either normoxia (FiO2=21%) or hyperoxia (FiO2=85%). Global changes of gene expression in the lung and ileum were analyzed by Illumina microarray.