遇见数据集

The strutural dynamics of EGFR Exon 19 mutants

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NIAID Data Ecosystem2026-03-14 收录
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Tyrosine kinase inhibtors are used to treat non-small cell lung cancers (NSCLC) driven by epidermal growth factor receptor (EGFR) mutations in the tyrosine kinase domain (TKD). We characterized the dynamics of purified EGFR exon 19 kinase domain mutants by HDX-MS with or withour erlotinib, one of the first-generation TKIs.

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2023-03-11
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