Cutaneous Rosai Dofman disease

Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis. RDD usually presents with massive, painless, bilateral cervical lymphadenopathy, with or without systemic symptoms.
Although, the skin represents the most common extranodal site, clinical and dermoscopic features of cutaneous RDD (CRDD) remain insufficiently described, based mainly on single observations. A better understanding of the CRDD is required to avoid diagnostic delays and unnecessary investigations.

Records of all patients diagnosed with cutaneous histiocytosis, from 2016 to 2024, at the Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia, were retrieved. Only patients with histopathologically confirmed CRDD were included. Dermoscopic images were independently evaluated by two dermatologists (NL and RT).
Nine cases of CRDD were identified.
This is the description of all cases included in the study.