Datasets were simulated according to the genetic and phenotype model described in METHODS. Meta-analysis was performed to combine 20 cohorts with 1500 individuals each. For each replicate, summary ass
BackgroundGlycated hemoglobin (HbA1c) measures the average blood sugar level over the past three months. As a vital biomarker of blood glucose levels, it is used to diagnose Type-2 diabetes mellitus (
The CFA11:41 Mb haplotype was determined by the genotype of the following SNVs: 41144469, 41161357, 41161441*, 41163558, 41166847, 41176819*, 41185205, 41192676, 41196587*, 41200012, 41204074, 4121562
Note: 1Meta-analysis in the Chinese studies excluding studies with different diagnostic criteria of obesity; 2Meta-analysis in the non-Chinese studies excluding studies with different diagnostic crite
Genotype imputation has become standard practice in modern genetic studies. As sequencing-based reference panels continue to grow, increasingly more markers are being well or better imputed but at the
