CuI-Catalyzed C–N Bond Formation and Cleavage for the Synthesis of Benzimidazo[1,2‑<i>a</i>]quinazoline Derivatives
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A copper(I)-catalyzed domino reaction of N-(2-benzimidazolyl)-2-aminobenzamide and 2-halogenated benzaldehyde has been studied. The procedure is based on a sequential CuI-catalyzed Ullmann reaction (C–N bond formation) and two bond cleavage reactions and provides an efficient strategy for the synthesis of benzimidazo[1,2-a]quinazolines catalyzed by CuI/l-proline.
创建时间：
2014-06-20
